Volume 28
Number 4
Sep 2020
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Original articles
E. Hosseini, H. Karimpour, F. Shahbazi

Background: Venous thromboembolism (VTE) is a leading cause of mortality in critically ill patients. Pharmacological thromboembolism prophylaxis is an effective way to prevent thrombosis.
Methods: A Padua risk assessment model was used to determine critically ill medical patients’ risk and the appropriateness of pharmacological prophylaxis.
Results: Our analysis included 139 patients. VTE prophylaxis was considered appropriate for 89.9% of the patients who received prophylaxis. Non-guideline-approved dosing of heparin was observed in 24.4% of patients. Despite having an indication, 12.8% of patients did not receive prophylaxis. Intravenous prophylaxis was used in 6.6 % of heparin receivers. Thrombosis occurred in 2.6% of all patients.
Conclusion: Although most patients received pharmacological VTE prophylaxis, inappropriate dosing of heparin and delays in appropriate pharmacological VTE prophylaxis were common for patients with cerebrovascular disease and tumours.


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